Epistasis Analysis Goes Genome-Wide
نویسندگان
چکیده
منابع مشابه
Epistasis Analysis Goes Genome-Wide
Epistasis, a term coined by William Bateson in 1909 [1], refers to the interdependence of mutations in their phenotypic effects. Let the phenotypic value of a trait relative to that of the wild type be fA and fB for mutants A and B, respectively, and let the phenotypic value of the corresponding double mutant be fAB. Although variation exists, epistasis is usually defined by ε = fAB − fAfB and ...
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ژورنال
عنوان ژورنال: PLOS Genetics
سال: 2017
ISSN: 1553-7404
DOI: 10.1371/journal.pgen.1006558